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The subjects were examined quite thoroughly prior to the onset of the study, then every six months for two years. In addition to answering questions about AAS use, the subjects also provided their diet and supplement history, training routine and background, were physically measured (including testicular volume) and blood work was drawn to assess the effect on the liver, lipids/cholesterol and other factors involved in cardiovascular health, heart function by echocardiography, endocrine hormones, glucose and insulin sensitivity, immune function, as well as prostate exams and semen analyses. This study incorporated as complete a workup as one can get without being abducted and probed by space aliens.

Seven subjects withdrew from the study due to buy anabolic steroids online emotional challenges or sexual dysfunction, leaving 13 who completed the two-year term. As would be expected, the subjects gained lean mass and lost fat mass, along with suppression of the pituitary hormones LH and FSH, resulting in smaller testicles (2 percent to 40 percent smaller); two of the subjects experienced azoospermia (no sperm) while two others had very low sperm counts.7,8,11 Most other hormones were unaffected by AAS use (including testosterone and estradiol, surprisingly), the exception being thyroid hormone. Both free T3 (the active form of thyroid hormone) and TSH (the regulatory hormone that controls thyroid hormone production) were lower, though remained in the normal range…yet the subjects still experienced apparent fat loss. Gynecomastia (bitch tits) occurred in five of the subjects.

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