Nevertheless, corticosteroids are constantly breaking down muscle tissue at a constant rate, though normal physiological functions should dictate a slow but steady rate. If an athlete or bodybuilder places his or her body within the proper parameters in nutrition and training, the individual’s body will offset the balance of anabolism and catabolism to favor that of anabolism, whereby more protein will be stored and constructed as muscle tissue than there is buy anabolic steroids being broken down (or catabolized) by glucocorticoids.
The introduction of anabolic steroids at supraphysiological levels into the body can shift the balance of anabolism to catabolism in vast favor of anabolism far beyond what the body could achieve naturally. It will not only increase the anabolic effects of steroids, but at the same time increase the suppressive effect of the catabolic effect of corticosteroids (glucocorticoids) by way of androgens causing glucocorticoids to be removed from their respective glucocorticoid receptors in muscle cells as demonstrated by studies. It has also been discovered through studies that androgens, such as Testosterone, will interfere with the DNA transcription process caused by glucocorticoid effects on the glucocorticoid receptors in muscle cells.